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Evolution: The Molecular Landscape

Cold Spring Harbor’s 74th Symposium
EVOLUTION
The Molecular Landscape
Edited by Bruce Stillman,
David Stewart, and
Jan Witkowski,
Cold Spring Harbor Laboratory

   
 

Evolution Chapter 13 Discussion Questions

DQ 13.1

The key finding from this chapter is that there are surprisingly large genetic differences between individuals from the same population. What are the implications of this diversity?

DQ 13.2

Why was it so hard to measure the extent of genetic diversity before the emergence of molecular biology? Is our understanding of the extent of genetic diversity now complete?

DQ 13.3

In a large sample from nature of an insect species, several variants are found with aberrant wing venation, unusual coloration, and so on. How can we determine whether these variants are due to genetic differences?

DQ 13.4

What is a gene? How was a gene defined in classical genetics? Discuss the difficulties in defining a gene in the light of our modern knowledge of genetics.

DQ 13.5

Sometimes, two different proteins are encoded by overlapping stretches of DNA, which are translated in different reading frames (see Fig. 13.2B). What might the evolutionary consequences be?

DQ 13.6

Box 13.3 described a variety of different kinds of genetic markers, which can be used in a variety of ways. What factors make each marker more or less suitable for different purposes?

DQ 13.7

Figure 13.17B shows how gene number and nucleotide diversity, π, tend to increase with genome size. Does the amount of DNA sequence per gene increase with genome size? In a diploid individual formed by random mating, does the total number of heterozygous sites increase with genome size?

 
 
 

 
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